Pubblicazioni del dott. Sergio Pandolfi su PubMed

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The use of the medical ozone in the immune challenge of multidrug resistant (MDR) bacteria and the role of mitochondria.
Chirumbolo S, Valdenassi L, Tirelli U, Pandolfi S, Franzini M. Microbes Infect. 2024 Jan-Feb;26(1-2):105242. doi: 10.1016/j.micinf.2023.105242. Epub 2023 Oct 28. PMID: 38380603 Free article. No abstract available.


The Mito-Hormetic Mechanisms of Ozone in the Clearance of SARS-CoV2 and in the COVID-19 Therapy.
Chirumbolo S, Varesi A, Franzini M, Valdenassi L, Pandolfi S, Tirelli U, Esposito C, Ricevuti G. Biomedicines. 2022 Sep 12;10(9):2258. doi: 10.3390/biomedicines10092258. PMID: 36140358 Free PMC article. Review.


Insights on the mechanisms of action of ozone in the medical therapy against COVID-19.
Chirumbolo S, Valdenassi L, Simonetti V, Bertossi D, Ricevuti G, Franzini M, Pandolfi S. Int Immunopharmacol. 2021 Jul;96:107777. doi: 10.1016/j.intimp.2021.107777. Epub 2021 May 11. PMID: 34020394 Free PMC article. Review.


COVID-19 Medical and Pharmacological Management in the European Countries Compared to Italy: An Overview.
Pandolfi S, Valdenassi L, Bjørklund G, Chirumbolo S, Lysiuk R, Lenchyk L, Doşa MD, Fazio S. Int J Environ Res Public Health. 2022 Apr 2;19(7):4262. doi: 10.3390/ijerph19074262. PMID: 35409942 Free PMC article. Review.


Oxygen-ozone therapy for myocardial ischemic stroke and cardiovascular disorders.
Pandolfi S, Chirumbolo S, Franzini M, Tirelli U, Valdenassi L. Med Gas Res. 2025 Mar 1;15(1):36-43. doi: 10.4103/mgr.MEDGASRES-D-23-00013. Epub 2024 Aug 31. PMID: 39217427 Free PMC article. Review.


Home pharmacological therapy in early COVID-19 to prevent hospitalization and reduce mortality: Time for a suitable proposal.
Pandolfi S, Chirumbolo S, Ricevuti G, Valdenassi L, Bjørklund G, Lysiuk R, Doşa MD, Lenchyk L, Fazio S. Basic Clin Pharmacol Toxicol. 2022 Feb;130(2):225-239. doi: 10.1111/bcpt.13690. Epub 2021 Dec 2. PMID: 34811895 Free PMC article. Review.


Cytokine profiles in COVID-19 patients undergoing adjunct ozone therapy: some comments.
Chirumbolo S, Pandolfi S, Franzini M, Valdenassi L. Inflammopharmacology. 2023 Dec;31(6):3363-3365. doi: 10.1007/s10787-023-01359-x. Epub 2023 Oct 13. PMID: 37831391.


Complications During Ozone Therapy as a Result of Malpractice and Lack of Guidelines.
Chirumbolo S, Pandolfi S, Valdenassi L, Chierchia M, Franzini M. Clin Neuroradiol. 2024 Sep;34(3):719-720. doi: 10.1007/s00062-024-01412-4. Epub 2024 Apr 23. PMID: 38652162 No abstract available.


Escaping from COVID-19 emergency accounting on previously infected subjects?
Chirumbolo S, Pandolfi S. J Med Virol. 2022 Jun;94(6):2352-2353. doi: 10.1002/jmv.27645. Epub 2022 Feb 8. PMID: 35112367 Free PMC article. No abstract available.


On reaching herd immunity during the COVID-19 pandemic and further issues.
Pandolfi S, Chirumbolo S. J Med Virol. 2022 Jan;94(1):24-25. doi: 10.1002/jmv.27322. Epub 2021 Sep 12. PMID: 34491592 Free PMC article. No abstract available.


Ozonated water in painful periodontitis and photo biomodulation (PBM) therapy: some comments.
Chirumbolo S, Franzini M, Pandolfi S, Valdenassi L. Lasers Med Sci. 2024 Jan 17;39(1):32. doi: 10.1007/s10103-024-03990-8. PMID: 38228996 No abstract available.


Ozone in the ischemia/reperfusion (I/R) injury. Lessons for ozone therapy in myocardial ischemia.
Chirumbolo S, Franzini M, Valdenassi L, Pandolfi S. Biomed Pharmacother. 2023 Nov;167:115482. doi: 10.1016/j.biopha.2023.115482. Epub 2023 Sep 15. PMID: 37717532 Free article. No abstract available.


Commentary: Ozone therapy as a novel complementary therapeutic approach in refractory idiopathic granulomatous mastitis.
Chirumbolo S, Franzini M, Pandolfi S, Tirelli U, Valdenassi L. Front Med (Lausanne). 2023 Dec 11;10:1272059. doi: 10.3389/fmed.2023.1272059. eCollection 2023. PMID: 38148915 Free PMC article. No abstract available.


Home therapy of COVID-19 at the earliest may greatly prevent hospitalization.
Pandolfi S, Chirumbolo S. Basic Clin Pharmacol Toxicol. 2021 Dec;129(6):395-396. doi: 10.1111/bcpt.13650. Epub 2021 Sep 26. PMID: 34494369 Free PMC article. No abstract available.


Medical use of adjunct oxygen-ozone therapy and its impact on the scientific literature to date.
Chirumbolo S, Valdenassi L, Pandolfi S, Tirelli U, Franzini M. Lancet Reg Health Am. 2024 Jun 8;35:100807. doi: 10.1016/j.lana.2024.100807. eCollection 2024 Jul. PMID: 38962066 Free PMC article. No abstract available.


Post-surgical wounds treated with ozone: a preliminary case series.
Franzini M, Valdenassi L, Tirelli U, Ricevuti G, Pandolfi S, Vaiano F, Chirumbolo S. Med Gas Res. 2024 Dec 1;14(4):225-227. doi: 10.4103/mgr.MEDGASRES-D-23-00017. Epub 2024 Mar 28. PMID: 39073331 Free PMC article. No abstract available.


Adjunct treatment with ozone to enhance therapy of knee osteoarthritis: preliminary results.
Valdenassi L, Chierchia M, Pandolfi S, Bellardi D, Chirumbolo S, Franzini M. Clin Rheumatol. 2024 Jun;43(6):2093-2101. doi: 10.1007/s10067-024-06972-x. Epub 2024 Apr 26. PMID: 38671261.


Ozone in the adjunct medical treatment. The round personality of a molecule with hormetic properties.
Chirumbolo S, Tirelli U, Franzini M, Pandolfi S, Ricevuti G, Vaiano F, Valdenassi L. Hum Exp Toxicol. 2023 Jan-Dec;42:9603271231218926. doi: 10.1177/09603271231218926. PMID: 38073286 Free article.


Insights into the use of oxygen-ozone therapy in ischemic cardiopathy and cardiovascular disease: a role for mitochondria?
Pandolfi S, Valdenassi L, Franzini M, Simonetti V, Chirumbolo S. Med Gas Res. 2024 Dec 1;14(4):164-166. doi: 10.4103/mgr.MEDGASRES-D-23-00007. Epub 2024 Mar 28. PMID: 40434379 Free PMC article. No abstract available.


The Role of Ozone as an Nrf2-Keap1-ARE Activator in the Anti-Microbial Activity and Immunity Modulation of Infected Wounds.
Franzini M, Valdenassi L, Pandolfi S, Tirelli U, Ricevuti G, Chirumbolo S. Antioxidants (Basel). 2023 Nov 8;12(11):1985. doi: 10.3390/antiox12111985. PMID: 38001838 Free PMC article.


Spermidine in the aging brain: mechanisms, preclinical evidence, and clinical perspectives.
Pandolfi S, Björklund G, Ghezzi C, Paone FM, Chirumbolo S. Mol Biol Rep. 2026 Apr 21;53(1):643. doi: 10.1007/s11033-026-11827-6. PMID: 42012729 Review.


Comments on “To clarify the safety profile of paracetamol for home-care patients with COVID-19: a real-world cohort study, with nested case-control analysis, in primary care”.
Chirumbolo S, Valdenassi L, Simonetti V, Pandolfi S. Intern Emerg Med. 2023 Apr;18(3):955. doi: 10.1007/s11739-023-03194-y. Epub 2023 Jan 10. PMID: 36626015 Free PMC article. No abstract available.


The biological activity of medical ozone in the hormetic range and the role of full expertise professionals.
Franzini M, Valdenassi L, Pandolfi S, Tirelli U, Ricevuti G, Simonetti V, Berretta M, Vaiano F, Chirumbolo S. Front Public Health. 2022 Sep 16;10:979076. doi: 10.3389/fpubh.2022.979076. eCollection 2022. PMID: 36187636 Free PMC article. No abstract available.


The Oxygen-Ozone Adjunct Medical Treatment According to the Protocols from the Italian Scientific Society of Oxygen-Ozone Therapy: How Ozone Applications in the Blood Can Influence Clinical Therapy Success via the Modulation of Cell Biology and Immunity.
Chirumbolo S, Valdenassi L, Tirelli U, Ricevuti G, Pandolfi S, Vaiano F, Galoforo A, Loprete F, Simonetti V, Chierchia M, Bellardi D, Richelmi T, Franzini M. Biology (Basel). 2023 Dec 11;12(12):1512. doi: 10.3390/biology12121512. PMID: 38132338 Free PMC article.


Letter to the Editor Regarding “Neuroprotective Effects of Coenzyme Q10 and Ozone Therapy on Experimental Traumatic Spinal Cord Injuries in Rats”.
Chirumbolo S, Franzini M, Tirelli U, Pandolfi S, Valdenassi L. World Neurosurg. 2024 Sep;189:495. doi: 10.1016/j.wneu.2024.05.039. PMID: 39252338 No abstract available.


Comments on the optimal use of medical ozone in clinics versus the Ozone High Dose Therapy (OHT) approach.
Franzini M, Valdenassi L, Pandolfi S, Ricevuti G, Tirelli U, Vaiano F, Chirumbolo S. Transl Med Commun. 2022;7(1):26. doi: 10.1186/s41231-022-00132-6. Epub 2022 Dec 5. PMID: 36533116 Free PMC article. No abstract available.


Estimating coronavirus disease 2019 (COVID-19)-caused deaths in hospitals and healthcare units: Do hospital-acquired infections play a role? Comments with a proposal.
Chirumbolo S, Simonetti V, Franzini M, Valdenassi L, Bertossi D, Pandolfi S. Infect Control Hosp Epidemiol. 2022 Jun;43(6):810-811. doi: 10.1017/ice.2021.122. Epub 2021 Mar 19. PMID: 33736720 Free PMC article. No abstract available.


Seasonality of COVID-19 deaths. Did social restrictions and vaccination actually impact the official reported dynamic of COVID-19 pandemic in Italy?
Chirumbolo S, Pandolfi S, Valdenassi L. Environ Res. 2022 Sep;212(Pt B):113229. doi: 10.1016/j.envres.2022.113229. Epub 2022 Apr 8. PMID: 35405125 Free PMC article. No abstract available.


The Problem of Home Therapy during COVID-19 Pandemic in Italy: Government Guidelines versus Freedom of Cure?
Fazio S, Cosentino M, Marino F, Pandolfi S, Zanolin E, Bellavite P. J Pharm Pharmacol Res. 2022 Aug 2;6(3):100-114. doi: 10.26502/fjppr.055. PMID: 37168835 Free PMC article.


Oxygen-ozone autohemotherapy against COVID-19 needs to fit highly experienced, customized, and standardized protocols to succeed.
Chirumbolo S, Franzini M, Simonetti V, Valdenassi L, Ricevuti G, Bertossi D, Pandolfi S. J Med Virol. 2021 May;93(5):2580-2582. doi: 10.1002/jmv.26806. Epub 2021 Jan 27. PMID: 33503267 Free PMC article. No abstract available.


Tesi sperimentale: “Università degli Studi di Pavia” – Master Universitario di II˚ livello in Ossigeno – Ozonoterapia

L’ossigeno ozonoterapia nel trattamento delle patologie del microcircolo e nella neuroprotezione. valutazione sperimentale del miglioramento del flusso e della ossigenazione cerebrale valutati mediante doppler trans-cranico e spettroscopia nirs in pazienti trattati con grande autoemo infusione (GAE).
Per visualizzare la Tesi

Valutazione Sperimentale

Valutazione sperimentale del miglioramento del flusso e della ossigenazione cerebrale valutati mediante doppler trans-cranico e spettroscopia nirs in pazienti trattati con grande autoemoinfusione di sangue ozonizzato
Per visualizzare l’articolo

Miglioramento del metabolismo e dell’ossigenazione celebrale tramite ozono terapia

Ozone Autohemotherapy Induces long-term cerebral metabolic changes in multiple sclerosis patient

Link a: Vedi pubblicazione scientifica inglese

Traduzione italiana: L’ossigeno Ozonoterapia mediante autoemoinfusione di sangue ozonizzato induce un miglioramento del metabolismo cerebrale nei pazienti affetti da sclerosi multiplas.

Link a: Vedi pubblicazione scientifica

Effetti dell’ossigeno ozono terapia nella funzionalità cardiaca in un paziente con un pregresso infarto del miocardio

Italiano:
articolo in ITALIANO

Inglese: Effects of oxygen ozone therapy on cardiac function Italiano

Improvement of Neurological

Inglese: Improvement of neurological conditions and recovery of the left ventricular ejection fraction subsequent to oxygen-ozone therapy through auto-hemoinfusion of ozonated blood (gae)

 

Italiano: Paziente di 76 anni con miglioramento delle condizioni neurologiche e recupero della frazione d’eiezione del ventricolo sinistro dopo ossigeno ozonoterapia mediante autoemoinfusione di sangue ozonizzato (gae)

Risultati del trattamento con ossigeno ozono terapia

Università degli studi di Pavia master di II° livello in Ossigeno Ozono Terapia dipartimento di medicina interna e terapia medica.

 

Miglioramento delle condizioni cardiache di un paziente critico di 76 anni, con pregresso infarto al miocardio e preparazione all’intervento chirurgico di ernia inguinale, trattato con GAE.

Insights on the mechanisms of action of ozone in the medical therapy against COVID-19

Aspetti salienti sui meccanismi di azione dell’ozono nella terapia medica contro la COVID-19

Italiano: scarica il pdf della pubblicazione scientifica tradotto in italiano

English: download original version from International Immunopharmacology Journal


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